Andy Benson Seminar Notes

Gave presentation at Michigan State University Microbiology & Molecular Genetics Department Seminar on December 3rd, 2012.

Talk was entitled “Assembly of the gut microbiome is shaped by convergence of genetic and environmental factors”

Andy is a professor in the Food Science & Technology Department at the University of Nebraska

See review article by Zhao 2013 in Nature Review Microbiolgy The gut microbiota and obesity: from correlation to causality

Other Papers of Interest include:

Human Microbiome Project Consortium 2012 Nature Paper Structure, function and diversity of the healthy human microbiome

Arumugam et al 2011 Enterotypes of the human gut microbiome

Jia et al 2008 Gut microbiota: a potential new territory for drug targeting

Cho & Blaser The human microbiome: at the interface of health and disease

Qin et al 2010 A human gut microbial gene catalogue established by metagenomic sequencing

Kuczynski et al 2012 Experimental and analytical tools for studying the human microbiome

Review from Eloe-Fadrosh & Rasko 2013 The Human Microbiome: From Symbiosis to Pathogenesis

Andy specifically referenced tools developed in Curtis Huttenhower’s Lab.

One of the goals of the research is to establish a human gut microbiome gene catalogue through Metagenomic sequencing

Gene by diet interactions were determined in mouse models and they are interested in expanding this study to cover the large amount of data they have on cattle gut microbiomes.

Some assemblers that were used on their data include: IDBA-UD, metaVelvet

Establishing a limit of detection using metagenomics techniques


03 December 2013